Basic Information
VIS ID
TVIS44009162
Fusion event
HTLV-1-LOC100506258 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
7477850/7456619 (Hg38)
End
7477850/7456619 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LOC100506258
Nearest miRNA
hsa-mir-210/Upstream/221782; hsa-let-7a-2/Downstream/1633693;
Nearest TSS
ENST00000527297/Upstream/15927; ENST00000534244/Downstream/4725;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/203615, chr11-CpG: 107/Downstream/56704
Upstream sequence
AAATGGCCACCCTCCATAAGTGGTAATGGTGATATCCTGAAATCAAGTTCACAGGTGAACAGATCTAATGTCCATTTTATTGTTCACTAAAGTTTAGGGT
Downstream sequence
CAGTTGAGAGTGGGTGATAAATATATGACTCTTCATTCATTATCTCTTTGGTATTTATATTTTTGACTTATTTTTTCAGAACTCCATTGGTCCCTATTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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