Basic Information
VIS ID
TVIS44009189
Fusion event
HTLV-1-LOC105369477 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
107130544/107259818 (Hg38)
End
107130544/107259818 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369477
Nearest miRNA
hsa-mir-10392/Upstream/3409838; hsa-let-7a-2/Downstream/4087939;
Nearest TSS
ENST00000527297/Upstream/241294; ENST00000529675/Downstream/56453;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/240341, chr11-CpG: 20/Downstream/197897
Nearby gene
CWF19L2(-66528) ;
Upstream sequence
ACAGAAAGCAGACCTTAATGGTGACTGGCAGACTCTTGTCCACTGTGCAGGGTATAGCTCCCTGGCTCCACTCCTGTCACCTCACCCCCAGCTGTCAAAT
Downstream sequence
TGCCTGGGAAACCGACTTGTCACCAGAAGATTCATGGCAAGCATGCAATTCAAACAGGAATCTGGGAGATGCTGCTGGTCTTATCCCTACTTCACTAGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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