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TVIS44009250
Basic Information
VIS ID
TVIS44009250
Fusion event
HTLV-1-TXNDC16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
52977363/52510645 (Hg38)
End
52977363/52510645 (Hg38)
Orient
-
Location type
Intronic
Target gene
TXNDC16
miRNAs that regulate target gene
hsa-mir-29c-3p
;
hsa-mir-10b-5p
;
hsa-mir-585-5p
;
hsa-mir-4316
;
hsa-mir-4710
;
hsa-mir-4722-5p
;
hsa-mir-6804-5p
;
hsa-mir-125a-3p
;
hsa-mir-6885-5p
;
hsa-mir-552-3p
;
hsa-mir-328-5p
;
hsa-mir-486-3p
;
hsa-mir-3622b-5p
;
hsa-mir-1827
;
hsa-mir-4532
;
hsa-mir-4768-3p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-5197-5p
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-7703
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-4252
;
hsa-mir-6776-5p
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-6742-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-3671
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-3163
;
hsa-mir-892c-3p
;
hsa-mir-4676-3p
;
hsa-mir-452-5p
;
hsa-mir-429
;
hsa-mir-200c-3p
;
hsa-mir-200b-3p
;
hsa-mir-5692a
;
hsa-mir-2909
;
hsa-mir-1296-5p
;
hsa-mir-1258
;
hsa-mir-6781-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6499-5p
;
hsa-mir-5693
;
hsa-mir-4512
;
hsa-mir-7160-3p
;
hsa-mir-6895-5p
;
hsa-mir-665
;
hsa-mir-6771-5p
;
hsa-mir-7977
;
hsa-mir-566
;
hsa-mir-7160-5p
;
hsa-mir-6720-3p
;
hsa-mir-6499-3p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-4537
;
hsa-mir-20b-3p
;
hsa-mir-17-3p
;
hsa-mir-4649-3p
;
hsa-mir-6746-5p
;
hsa-mir-5690
;
hsa-mir-2114-5p
;
hsa-mir-5588-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-596
;
hsa-mir-125b-2-3p
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-30b-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-30c-2-3p
;
hsa-mir-3122
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-3913-5p
;
hsa-mir-3974
;
hsa-mir-4433a-3p
;
hsa-mir-4457
;
hsa-mir-4459
;
hsa-mir-450a-1-3p
;
hsa-mir-4728-5p
;
hsa-mir-4767
;
hsa-mir-513b-5p
;
hsa-mir-6087
;
hsa-mir-6089
;
hsa-mir-624-3p
;
hsa-mir-6513-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6788-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-887-5p
Nearest miRNA
hsa-mir-208a/Upstream/2210699; hsa-mir-1185-1/Downstream/1437782;
Nearest TSS
ENST00000550708/Upstream/39971;
ENST00000555622/Downstream/41860;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/195354
,
chr14-CpG: 126/Downstream/41675
Upstream sequence
tcatctaaattaacttctgagtagacggattaagtgacttcttaaaacttttccttcatacttggctgcaatgtttggattacttataatacacatgcac
Downstream sequence
cactttTATATTTTAAAAAAGACATACTGAATGAGAATATCTACTAAAGATTTTACATGTGCTCAACACAACCCTTCAACTTTTCGGAGAGAACAGTTTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL6
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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