Basic Information
VIS ID
TVIS44009274
Fusion event
HTLV-1-AAGAB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
End
67503451/67211113 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/714079; hsa-mir-11181/Downstream/1590737;
Upstream sequence
GCCAGATACCTGGTCATACAGAGATATCAAAAGAGAGAAACTTCGCAGTGTCCTTCCTTCTTCCTTTCACTTGGGAAGATCTGCCTTTTAAACTGGGATG
Downstream sequence
AAGCCTCAAATGTGGCCTGCTAGGCTGTAGCCTGCAGATTTCTGGAGCCTGACTCTCGCCACGGAGGCAGTCATATGTAGCTATCAACCCAGTACCTCTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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