Basic Information
VIS ID
TVIS44009276
Fusion event
HTLV-1-PKM integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
End
72521952/72229611 (Hg38)
Orient
-
Location type
UTR5
Target gene
miRNAs that regulate target gene
hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-326 ; hsa-mir-122-5p ; hsa-mir-30a-5p ; hsa-mir-1301-3p ; hsa-mir-935 ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-296-3p ; hsa-mir-766-3p ; hsa-mir-769-5p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-324-3p ; hsa-mir-328-3p ; hsa-mir-330-3p ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-30c-5p ; hsa-mir-92a-3p ; hsa-mir-23a-3p ; hsa-mir-1260b ; hsa-mir-3187-3p ; hsa-mir-218-5p ; hsa-mir-6730-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-6515-5p ; hsa-mir-4727-3p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-4668-5p ; hsa-mir-6822-3p ; hsa-mir-504-3p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-3659 ; hsa-mir-6804-5p ; hsa-mir-17-3p ; hsa-mir-4254 ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-4650-5p ; hsa-mir-1296-3p ; hsa-mir-4694-3p ; hsa-mir-338-3p ; hsa-let-7a-5p ; hsa-mir-369-3p ; hsa-mir-184 ; hsa-mir-1205 ; hsa-mir-1238-5p ; hsa-mir-1285-3p ; hsa-mir-1286 ; hsa-mir-1302 ; hsa-mir-153-5p ; hsa-mir-1587 ; hsa-mir-185-3p ; hsa-mir-185-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-3135b ; hsa-mir-3144-5p ; hsa-mir-3176 ; hsa-mir-3179 ; hsa-mir-3187-5p ; hsa-mir-3191-3p ; hsa-mir-330-5p ; hsa-mir-3620-5p ; hsa-mir-3652 ; hsa-mir-378g ; hsa-mir-3909 ; hsa-mir-3922-3p ; hsa-mir-3945 ; hsa-mir-4253 ; hsa-mir-4263 ; hsa-mir-4271 ; hsa-mir-4298 ; hsa-mir-4306 ; hsa-mir-432-3p ; hsa-mir-4430 ; hsa-mir-4436a ; hsa-mir-4481 ; hsa-mir-4486 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-4534 ; hsa-mir-4644 ; hsa-mir-4648 ; hsa-mir-4651 ; hsa-mir-4652-5p ; hsa-mir-4656 ; hsa-mir-4675 ; hsa-mir-4722-5p ; hsa-mir-4725-3p ; hsa-mir-4731-5p ; hsa-mir-4741 ; hsa-mir-4745-5p ; hsa-mir-4747-5p ; hsa-mir-4758-5p ; hsa-mir-491-5p ; hsa-mir-5000-3p ; hsa-mir-5001-5p ; hsa-mir-5189-5p ; hsa-mir-5192 ; hsa-mir-5196-5p ; hsa-mir-552-3p ; hsa-mir-576-5p ; hsa-mir-5787 ; hsa-mir-6085 ; hsa-mir-608 ; hsa-mir-612 ; hsa-mir-637 ; hsa-mir-6732-5p ; hsa-mir-6752-5p ; hsa-mir-6756-5p ; hsa-mir-6758-5p ; hsa-mir-6766-5p ; hsa-mir-6780a-3p ; hsa-mir-6780b-5p ; hsa-mir-6810-5p ; hsa-mir-6813-5p ; hsa-mir-6829-5p ; hsa-mir-6842-5p ; hsa-mir-6852-3p ; hsa-mir-6856-5p ; hsa-mir-6860 ; hsa-mir-6862-5p ; hsa-mir-6894-5p ; hsa-mir-7110-5p ; hsa-mir-7154-3p ; hsa-mir-762 ; hsa-mir-764 ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-8077 ; hsa-mir-873-5p ; hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-10393/Upstream/2150143; hsa-mir-11181/Downstream/357606;
Upstream sequence
AGTACGTAGATTAAGAAGCCAAGGGATGCCCTTACATGACTGAGTCTTTAAATGATCTTCAGACTGGAAGGTGCTTTCCTGCATCTTCTAATCCAGTGTG
Downstream sequence
CTTGCCACCTGGTGAGACCTTACGAGGCTTCCTGTCCCCCTCCCTCCCACAGCAGGAAGCTCGTACCCCACTCCCAGCATTACAGGAGATACATTTTAAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate