Basic Information
VIS ID
TVIS44009294
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8777823/8874506 (Hg38)
End
8777823/8874506 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1253/Upstream/687502; hsa-mir-10226/Downstream/3207393;
Nearest TSS
ENST00000595228/Upstream/6829; ENST00000585297/Downstream/7363;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/75000, chr17-CpG: 35/Downstream/13647
Nearby gene
PIK3R5(-4410) ;
Upstream sequence
GGCTTCTTGCCCTGGAGGCTGTGGGAGAGCCCTTTCCCCGGGGGGAGGCATGACTGGGATGCCAGGGACTTCAAGGAGAGGTCTGAAGATGGTGATAGAC
Downstream sequence
CACTACCTTCCGGCCCCTAGAAGAAGCTCCCAGCTACCTGAGGAGAACAAAGAGGTGTAAGCCATTGTGTCTGGAGGAGCCCCCTCTCGGTAAGGCTTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate