Basic Information
VIS ID
TVIS44009301
Fusion event
HTLV-1-FAM20A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
66589220/68593079 (Hg38)
End
66589220/68593079 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM20A
Nearest miRNA
hsa-mir-10226/Upstream/168531; hsa-mir-1250/Downstream/506463;
Nearest TSS
ENST00000595228/Upstream/1240; ENST00000591754/Downstream/7517;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/80002, chr17-CpG: 135/Downstream/6898
Upstream sequence
TGCCATCTCCATAGCACTTCAAACTCAGTTCTGTCCTGATTTCACATTTCAACTATAGGATGTTCTGCCAAGTGACAGGGCACAAAAAGAGCTAAGCCTC
Downstream sequence
TTTTCTGTACTGTGGTTTTCATTAAGTGCATATGTGTGTGCCTGCCTATAATAACAGGTAAGAACTTATGTCTAGTAACTTCTGTTCTGCTACAGCTGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate