Basic Information
VIS ID
TVIS44009306
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
4818935/4818936 (Hg38)
End
4818935/4818936 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-6718/Upstream/933504; hsa-mir-1-2/Downstream/1021759;
Nearest TSS
ENST00000575820/Upstream/363601; ENST00000583985/Downstream/185588;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/363289, chr18-CpG: 80/Downstream/377308
Upstream sequence
CCCCGATGGAGGCAGTCAGCCAATCCTATTTAGAATGGGCTCAAGAAATGGGGAGTGTTCAATTCCACTTAGTCCCTTGTCAAATTCAATGGGAACCAAC
Downstream sequence
TTTACAAAAAAGCTAAGTTACCTCTGACTTGAACCCATGATAAATGCTCAATACACAATTTACTAACAAAATTTCTACCAAAGCACTTTTTATGTCATTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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