Basic Information
VIS ID
TVIS44009328
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh37/hg19
Start
30842325/30351418 (Hg38)
End
30842325/30351418 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC110120875 ; ZNF536
Nearest miRNA
hsa-mir-10395/Upstream/9952064; hsa-let-7e/Downstream/4771282;
Nearest TSS
ENST00000633603/Upstream/122703; ENST00000355537/Downstream/20994;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/122355, chr19-CpG: 90/Downstream/23358
Nearby gene
ZNF536(+20975) ;
Upstream sequence
TGCTTCCAGTATATGGTTTCAAAGAATGCACTTTTTGGACAATATCTAGTTACTGGGTAGTGAATTAATAGAGTTAAGGGTTCTGATGCAATTCACATAT
Downstream sequence
AGGTCAATTACATGCGCCAACATCTGCTCTGTCACTATCATTTGCATATAGCATTCATATGTTAATGATGCCTCTTTTTACTCAAGTAATATATTTAAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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