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TVIS44009331
Basic Information
VIS ID
TVIS44009331
Fusion event
HTLV-1-NOL10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
10749835/10609709 (Hg38)
End
10749835/10609709 (Hg38)
Orient
-
Location type
Intronic
Target gene
NOL10
miRNAs that regulate target gene
hsa-mir-148b-3p
;
hsa-mir-124-3p
;
hsa-mir-935
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-6883-5p
;
hsa-mir-4728-5p
;
hsa-mir-6785-5p
;
hsa-mir-149-3p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-3202
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-7515
;
hsa-mir-6783-5p
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-4428
;
hsa-mir-550b-2-5p
;
hsa-mir-1227-3p
;
hsa-mir-4480
;
hsa-mir-4279
;
hsa-mir-525-5p
;
hsa-mir-520a-5p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-3925-3p
;
hsa-mir-766-3p
;
hsa-mir-4264
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-622
;
hsa-mir-122-3p
;
hsa-mir-4422
;
hsa-mir-6835-3p
;
hsa-mir-1224-3p
;
hsa-mir-122-5p
;
hsa-mir-1304-3p
;
hsa-mir-1307-3p
;
hsa-mir-199a-3p
;
hsa-mir-199b-3p
;
hsa-mir-222-5p
;
hsa-mir-3129-5p
;
hsa-mir-3135b
;
hsa-mir-3652
;
hsa-mir-3664-5p
;
hsa-mir-4430
;
hsa-mir-4638-5p
;
hsa-mir-4639-3p
;
hsa-mir-4746-3p
;
hsa-mir-4797-3p
;
hsa-mir-504-3p
;
hsa-mir-6722-5p
;
hsa-mir-6794-3p
;
hsa-mir-936
Nearest miRNA
hsa-mir-4261/Upstream/417038; hsa-mir-10b/Downstream/930896;
Nearest TSS
ENST00000437798/Upstream/20543;
ENST00000607781/Downstream/61981;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/83070
,
chr2-CpG: 46/Downstream/79889
Upstream sequence
aaaGGACTTCATGTCGGAAGGAGCACATGAGCAAGCTAGGAAAATCACAGGCATCTTCTGAAGCCGAGAGAGTTGAGGCCCTTGTAACTACAGGGGTATC
Downstream sequence
TGCTTCCAGTGAGTCATAAACCTGCAAATGCAAAGCTCTATCAGATAATGGTGTACTCCCTAAAACAGCAATCTTTTCTTTTCTAGACGAGATCAAAGTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL6
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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