Basic Information
VIS ID
TVIS44009369
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
167028327/166171817 (Hg38)
End
167028327/166171817 (Hg38)
Orient
+
Location type
ncRNA_intronic
Nearest miRNA
hsa-mir-128-1/Upstream/5763935; hsa-mir-10b/Downstream/2411126;
Nearest TSS
ENST00000437798/Upstream/22603; ENST00000409043/Downstream/33422;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/217501, chr2-CpG: 31/Downstream/204061
Nearby gene
RN7SKP152(+8835) ;
Upstream sequence
CCATGGGAATTTGCTATAAGAACATTCTCCTTAGTAGAAATAATTTTTTTATTGTGAAACCATCACTACAAAACTTCTTTATAATGTTTCCTTTATTTTT
Downstream sequence
CTGTGGAAGAAGGTGCTCTATAGAGAGTCAGTAAAATTACTAGCCTTCATATTGGTTTAATATCTGCAAATGGAATTAAGACACTTTAGTGTGCCCTTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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