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TVIS44009372
Basic Information
VIS ID
TVIS44009372
Fusion event
HTLV-1-NCKAP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
183871345/183006617 (Hg38)
End
183871345/183006617 (Hg38)
Orient
+
Location type
Intronic
Target gene
NCKAP1
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-142-3p
;
hsa-mir-30a-5p
;
hsa-mir-18b-5p
;
hsa-mir-132-3p
;
hsa-mir-4459
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-1273e
;
hsa-mir-582-5p
;
hsa-mir-101-3p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6878-5p
;
hsa-mir-25-5p
;
hsa-mir-658
;
hsa-mir-655-5p
;
hsa-mir-6087
;
hsa-mir-4537
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-219b-3p
;
hsa-mir-1247-3p
;
hsa-mir-6871-5p
;
hsa-mir-302f
;
hsa-mir-6828-5p
;
hsa-mir-922
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-548e-5p
;
hsa-mir-6818-3p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-629-3p
;
hsa-mir-498
;
hsa-mir-6867-3p
;
hsa-mir-4713-5p
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-4284
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-1304-3p
;
hsa-mir-1281
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-939-3p
;
hsa-mir-4485-5p
;
hsa-mir-6890-3p
;
hsa-mir-1200
;
hsa-mir-3653-5p
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-660-3p
;
hsa-mir-7108-3p
;
hsa-mir-4258
;
hsa-mir-335-3p
;
hsa-mir-1305
;
hsa-mir-576-5p
;
hsa-mir-4775
;
hsa-mir-5681b
;
hsa-mir-95-5p
;
hsa-mir-3163
;
hsa-mir-590-3p
;
hsa-mir-3662
;
hsa-mir-4684-5p
;
hsa-mir-3675-3p
;
hsa-mir-6771-3p
;
hsa-mir-548ay-3p
;
hsa-mir-548at-3p
;
hsa-mir-548as-3p
;
hsa-mir-548t-3p
;
hsa-mir-548ap-3p
;
hsa-mir-548aa
;
hsa-mir-548c-3p
;
hsa-mir-34c-3p
;
hsa-mir-1972
;
hsa-mir-383-5p
;
hsa-mir-4650-5p
;
hsa-mir-4772-5p
;
hsa-mir-20a-3p
;
hsa-mir-3913-3p
;
hsa-mir-4732-3p
;
hsa-mir-489-3p
;
hsa-mir-544a
;
hsa-mir-6719-3p
;
hsa-mir-942-5p
Nearest miRNA
hsa-mir-10b/Upstream/1700965; hsa-mir-1244-1/Downstream/1372358;
Nearest TSS
ENST00000437798/Upstream/41853;
ENST00000342619/Downstream/31855;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/139252
,
chr2-CpG: 98/Downstream/31057
Upstream sequence
caatcctctcaatatctctatgcaatcacgttccccattttaGTGAAAATAAATTCCATAAAGCCTGGGTGAAAGAGGTCAACTACAACAATGAAGAACA
Downstream sequence
AAAGTGTCTACAACTCTCTTGCTTCAACTACAAAAAATGCTACATTTTAGTTCCTAAAGTGAGGGAGAGTAGATACTACCAAAAATTATTAATATCTAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL6
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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