Basic Information
VIS ID
TVIS44009380
Fusion event
HTLV-1-LINC01937 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
239652683/238744042 (Hg38)
End
239652683/238744042 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2J
Target gene
LINC01937
Nearest miRNA
hsa-mir-10b/Upstream/1233054; hsa-mir-149/Downstream/324775;
Nearest TSS
ENST00000437798/Upstream/23718; ENST00000448943/Downstream/45674;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/110130, chr2-CpG: 293/Downstream/102413
Nearby gene
TWIST2(+103990) ;
Upstream sequence
CAACAACGGACATGGAGACCTCAAACACCGGGTATGCCGGAATGCCCTGCACAGACGGCACTCTCCAGTGTGAAGACGACAAAGCCAGCCTCTGGATTTT
Downstream sequence
GTGTGTGTGTGTGTGTTTTATTTTTTAAAAATTAttttactttttcataagttattggaatacagttggtgtttggttacatgagtacgttctttagcgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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