Basic Information
VIS ID
TVIS44009391
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
16058563/14686242 (Hg38)
End
16058563/14686242 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA21A
Nearest miRNA
hsa-mir-10396a/Upstream/961968; hsa-let-7c/Downstream/1852847;
Nearest TSS
ENST00000624081/Upstream/27421; ENST00000430391/Downstream/67220;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/302477, chr21-CpG: 171/Downstream/377933
Nearby gene
LOC388813(-43135) ;
Upstream sequence
gattacaggcatgcaccaccacactcagctaatttttgtatttttagtagagatagggtttcaccatgttggccaggatggtctcgatttcctgaccttg
Downstream sequence
tgatctgcccacctcagcctcccaatgtgctgagattacaggtgtgaCATAATTATTCTTAATTAACCATTTTGTTGTTTGTGGTCTTATAAAATCTTTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate