Basic Information
VIS ID
TVIS44009400
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
33521980/33125994 (Hg38)
End
33521980/33125994 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1286/Upstream/1504463; hsa-let-7a-3/Downstream/310588;
Nearest TSS
ENST00000624155/Upstream/17465; ENST00000434741/Downstream/38069;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/67526, chr22-CpG: 20/Downstream/524374
Nearby gene
SYN3(-67603) ;
Upstream sequence
ctgccaccacactcggcaaatttttgtatttttaatagagacggggtttcactgtgttggcgaggctggtctcgaattcctgactttcgacaatccaccc
Downstream sequence
gactcagcctctcaaagtgctgggattacaggcgtgagccacagcgcccggcTGGAATTTGGATTATTTCTATAACCTTGAGATAAGAAATCCTAGGGCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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