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TVIS44009433
Basic Information
VIS ID
TVIS44009433
Fusion event
HTLV-1-ZBTB38 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q23
Reference genome
GRCh37/hg19
Start
141122743/141403901 (Hg38)
End
141122743/141403901 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZBTB38
miRNAs that regulate target gene
hsa-mir-30b-5p
;
hsa-mir-26b-5p
;
hsa-mir-21-5p
;
hsa-mir-877-3p
;
hsa-mir-877-5p
;
hsa-mir-155-5p
;
hsa-mir-3973
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548j-5p
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548bb-5p
;
hsa-mir-527
;
hsa-mir-518a-5p
;
hsa-mir-548aw
;
hsa-mir-4314
;
hsa-mir-513a-5p
;
hsa-mir-107
;
hsa-mir-103a-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-3192-5p
;
hsa-mir-4646-5p
;
hsa-mir-204-3p
;
hsa-mir-34b-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-10a-3p
;
hsa-mir-7702
;
hsa-mir-302c-5p
;
hsa-mir-151a-3p
;
hsa-mir-3143
;
hsa-mir-5003-3p
;
hsa-mir-6071
;
hsa-mir-6828-3p
;
hsa-mir-4753-3p
;
hsa-mir-130b-5p
;
hsa-mir-4778-5p
;
hsa-mir-2115-3p
;
hsa-mir-216b-5p
;
hsa-mir-8087
Nearest miRNA
hsa-let-7g/Upstream/6965995; hsa-mir-1224/Downstream/10161975;
Nearest TSS
ENST00000440867/Upstream/1083;
ENST00000509813/Downstream/22215;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/1065
,
chr3-CpG: 16/Downstream/82796
Upstream sequence
tgtcaaccactttgtgggtgtttgacttatgtgttcaatatgtgctaattgcagttattattGTTGCTAAAAGATGAAATCCTAGCAGCTAGTCATGGGA
Downstream sequence
CACTGCACTTTTTTTTTCTTTTTAGATCTTGATGTGGAAGAAATGGAGGACTCAGAACCAAGGATTTCCAAGTGATTTCTTCCAAAGCACAGGAATCTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL6
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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