Basic Information
VIS ID
TVIS44009443
Fusion event
HTLV-1-STX18-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
4591086/4589359 (Hg38)
End
4591086/4589359 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
STX18-AS1
Nearest miRNA
hsa-mir-4800/Upstream/2339203; hsa-mir-12113/Downstream/1333916;
Nearest TSS
ENST00000502981/Upstream/46941; ENST00000608184/Downstream/60065;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/13638, chr4-CpG: 41/Downstream/263527
Upstream sequence
TAATCTGAGGAACTGAGGCAGCATGAGAGAAGGTGTATTCACCTGCCTTGCTGTGACAACACACAGCCTTTCCCATGTGCACATGGAGAGAGGGAGTTCT
Downstream sequence
TTGGTGTCTCTTCCTCttcttcttctttttttttttttcttggcgatggagttttgctcttgtcgcccaggctggagtgcaatggtgcaatcttggctca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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