Basic Information
VIS ID
TVIS44009465
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
56538746/55672579 (Hg38)
End
56538746/55672579 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/2959832; hsa-mir-1243/Downstream/5250040;
Nearest TSS
ENST00000502981/Upstream/35881; ENST00000504250/Downstream/147240;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/36081, chr4-CpG: 44/Downstream/120881
Nearby gene
NMU(-36281) ;
Upstream sequence
attggtcactggtgccttatttagttcctttggtgaagtcatgttttcctggatggtcttgatgcttatggatgtttgtcagtatctgggaattgaagag
Downstream sequence
ttaggtatttatagtagtcttcacagcgtagggttgtttgtacccatccttcttgggaaggctttccaggtattctaaaggacttgggagttgtgatcta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate