Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene7633580176158733762345367621404076283780762056697621591976192944762026427623316976238668762032627620473376223376762247947621899776219832762174017621760076247267
Basic Information
VIS ID
TVIS44009471
Fusion event
HTLV-1-FAM47E integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
77168420/76247267 (Hg38)
End
77168420/76247267 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM47E
miRNAs that regulate target gene
hsa-mir-30e-3p
Nearest miRNA
hsa-mir-12113/Upstream/9970339; hsa-mir-1243/Downstream/326301;
Nearest TSS
ENST00000502981/Upstream/10998; ENST00000606246/Downstream/4433;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/33043, chr4-CpG: 54/Downstream/4167
Upstream sequence
tattctagatatttcatataatggagttatacactatatgtccttttgcatttgacttctttcacttagcatgttttcagggttaatccatgttataact
Downstream sequence
tatcaaaatttcattctttttatgaataattttccatgtatgtatatgccacattttgtttattaattcatctgttggtggacacttgggttcttatcac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate