Basic Information
VIS ID
TVIS44009476
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
111675384/110754228 (Hg38)
End
111675384/110754228 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/1265433; hsa-mir-1243/Downstream/106354;
Nearest TSS
ENST00000502981/Upstream/112105; ENST00000512794/Downstream/40175;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/114576, chr4-CpG: 120/Downstream/1391086
Nearby gene
PITX2(-112105) ;
Nearest cancer related gene
PITX2(OG, -112105) ;
Upstream sequence
ttgaaagcactggggccatggcaatgaacaaaacagacaaaaaatctctcccctcatggataacatggggagatagaaaataaacaagaaaaatataaag
Downstream sequence
catgttagcaaaaaatgctaagaagaaaaataaagcagggcaggcgggttggaaggttcaaggagagttatgaaatgttagataaggccgacagggaagg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate