Basic Information
VIS ID
TVIS44009509
Fusion event
HTLV-1-LINC02058 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
92270617/92934910 (Hg38)
End
92270617/92934910 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5B ; FRA5D
Target gene
LINC02058
Nearest miRNA
hsa-mir-10397/Upstream/2918190; hsa-mir-103a-1/Downstream/685786;
Nearest TSS
ENST00000502646/Upstream/108655; ENST00000512697/Downstream/4681;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1553797, chr5-CpG: 183/Downstream/635623
Nearby gene
NR2F1-AS1(No orient, 474445)
Upstream sequence
ATTTTTTTCTTTCAGAGTGCAAGAAATTTAAGATTAAAGCTCCTGAAAGCAGCTCACTATTGATAGGGAGGGGATAGAGAGCATATCTGAGTTCTCTACA
Downstream sequence
TTTGCTTATTCAAAAATATGCAAACCACATTAAAATTCCAATTCATATTCAAAATCTCAGTGTAGCGTGGGAATTTTCTTTTTAaactatcacgaaagac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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