Basic Information
VIS ID
TVIS44009527
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
28624211/28656434 (Hg38)
End
28624211/28656434 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3143/Upstream/1508746; hsa-mir-10398/Downstream/1927898;
Nearest TSS
ENST00000381078/Upstream/7368; ENST00000444986/Downstream/182572;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/20916, chr6-CpG: 21/Downstream/129658
Nearby gene
ZBED9(No orient, 69099)
Upstream sequence
AAAATCTTCACATGGTTTATTCTTAGGCTGTGATCAATAACCTCAGTAATTTGAAATAAAATACATCATGGTGGGTAGACAGAAATTTAACAGTGATTCT
Downstream sequence
CTCTTCTTTCTTGTCTGTATTGGGCAAACCTGGGAAAGTTTAAACATTCAAGGGAGGAAATCTGGCAGTGTTTGGCAAGAATCTCTAAAATACGAAGTAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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