Basic Information
VIS ID
TVIS44009556
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
42303409/42263810 (Hg38)
End
42303409/42263810 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1183/Upstream/5344378; hsa-mir-10399/Downstream/887085;
Nearest TSS
ENST00000635602/Upstream/25940; ENST00000432845/Downstream/442637;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/25955, chr7-CpG: 19/Downstream/229667
Nearby gene
GLI3(-26791) ;
Nearest cancer related gene
GLI3(OG, -26791) ;
Upstream sequence
gtgctgggattacaggcgtgagccaccgcacccCACCAGATCTTGATGCCTTTTGAAATTCCCCTAGCTGTATGCTGCAGAGGCTGCAAGTGTCTGGTGG
Downstream sequence
GGTTAGATCAGTCTTTTTTGTCCCATATATCAGGATATTTTTCTGCTATGAAACATacaacaacaacaacaaaaacagcaacgaccacaacaaAACAGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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