Basic Information
VIS ID
TVIS44009573
Fusion event
HTLV-1-MICU3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
GRCh37/hg19
Start
16892842/17035333 (Hg38)
End
16892842/17035333 (Hg38)
Orient
-
Location type
Intronic
Target gene
MICU3
Nearest miRNA
hsa-mir-124-1/Upstream/2181823; hsa-mir-10400/Downstream/646245;
Nearest TSS
ENST00000518652/Upstream/7755; ENST00000517398/Downstream/28797;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/7503, chr8-CpG: 147/Downstream/120594
Upstream sequence
tgtttttattagcagtgtgagaacagactaaCAGAgtaaatggatactggtagaggggggtgctgttgtaaagataaccaaaaatgtggaagtgactttg
Downstream sequence
gaactgggtaataggcagaggttggaacagtttggagggcttagaagaaaacacaaaaatatgggaaagtttggaacttcctacagacttgttgaatggc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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