Basic Information
VIS ID
TVIS44009606
Fusion event
HTLV-1-MSMP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
35753185/35753188 (Hg38)
End
35753185/35753188 (Hg38)
Orient
-
Location type
Exonic
Target gene
MSMP
Nearest miRNA
hsa-mir-101-2/Upstream/20193; hsa-let-7a-1/Downstream/1070351;
Nearest TSS
ENST00000422679/Upstream/3897; ENST00000574939/Downstream/1081;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/3908, chr9-CpG: 37/Downstream/3763
Upstream sequence
ATCAGTTGAGTTTAGCTGGAGTGGGGAGCAGGAGCCCCAGGAACAGGGGTGTTGGCTGAGCCCCATTCTGGGTCAGGCCCTCCCCCTTTGCAGGGCAGCC
Downstream sequence
GAGGGTCAGATTTTTGCACCAAGGAGAACTGGCAGGTTCCTGCCTCCTGACGTACCTCACACCCAGCCGGGAAGTCGATGGGATGCTGGGACCTGGGGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate