Basic Information
VIS ID
TVIS44009618
Fusion event
HTLV-1-LOC105376244 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
120598312/117836034 (Hg38)
End
120598312/117836034 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
LOC105376244
Nearest miRNA
hsa-let-7a-1/Upstream/3626505; hsa-mir-12126/Downstream/2408945;
Nearest TSS
ENST00000422679/Upstream/52586; ENST00000456032/Downstream/61222;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/90670, chr9-CpG: 97/Downstream/1532774
Nearby gene
TLR4(+118543) ;
Upstream sequence
gtcataacaaaagagaaatctgctagtgctatgagtcaaaatagaactataaatgagagtagaaatgcatgagctaatactgctgctggggtaagggtgg
Downstream sequence
cccttaaactagggactagggtgtttaacacatattcagaaacagaagacatgaccttgggctcaccagaggtctacctgagaattgtaaaatccattaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate