Basic Information
VIS ID
TVIS44009637
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
133486552/134352522 (Hg38)
End
133486552/134352522 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/182244; hsa-mir-105-1/Downstream/187663;
Nearest TSS
ENST00000429181/Upstream/115475; ENST00000370800/Downstream/20731;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/115074, chrX-CpG: 52/Downstream/20582
Nearby gene
PHF6(+20790) ;
Nearest cancer related gene
PHF6(TSG, +20790) ;
Upstream sequence
gaggttgcagtgagcagaaatcacgccactgcactccagcctgagggacagtgtgagatcctgtctcaaaaaaaaaaaaaaaaaaaagaaaagaaaggaa
Downstream sequence
ggaaggcaggaaggaaggtaggagagaaggaaggaaggaagattctcaactatgtggaaagtaagcaacatatttctaaataatgaatgggtcagacagt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate