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TVIS44009649
Basic Information
VIS ID
TVIS44009649
Fusion event
HTLV-1-MSI2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
55531376/57454015 (Hg38)
End
55531376/57454015 (Hg38)
Orient
-
Location type
Intronic
Target gene
MSI2
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-652-3p
;
hsa-mir-484
;
hsa-mir-1273e
;
hsa-mir-4766-5p
;
hsa-mir-203a-3p
;
hsa-mir-4282
;
hsa-mir-3163
;
hsa-mir-3688-3p
;
hsa-mir-8076
;
hsa-mir-5580-3p
;
hsa-mir-338-5p
;
hsa-mir-3924
;
hsa-mir-3680-5p
;
hsa-mir-4798-3p
;
hsa-mir-2355-3p
;
hsa-mir-676-3p
;
hsa-mir-6500-5p
;
hsa-mir-4633-3p
;
hsa-mir-6502-5p
;
hsa-mir-1301-5p
;
hsa-mir-610
;
hsa-mir-708-5p
;
hsa-mir-3139
;
hsa-mir-28-5p
;
hsa-mir-190a-3p
;
hsa-mir-202-3p
;
hsa-mir-7162-3p
;
hsa-mir-383-3p
;
hsa-mir-5011-5p
;
hsa-mir-410-3p
;
hsa-mir-4678
;
hsa-mir-497-3p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7d-5p
;
hsa-let-7e-5p
;
hsa-mir-4500
;
hsa-let-7f-5p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-let-7a-5p
;
hsa-mir-4458
;
hsa-mir-98-5p
;
hsa-mir-3165
;
hsa-mir-3689d
;
hsa-mir-3911
;
hsa-mir-3975
;
hsa-mir-4302
;
hsa-mir-4519
;
hsa-mir-4695-5p
;
hsa-mir-6134
;
hsa-mir-6499-3p
;
hsa-mir-6851-5p
;
hsa-mir-6880-5p
;
hsa-mir-6894-5p
;
hsa-mir-7154-3p
;
hsa-mir-765
;
hsa-mir-766-5p
;
hsa-mir-7847-3p
;
hsa-mir-8071
Nearest miRNA
hsa-mir-10226/Upstream/562660; hsa-mir-1250/Downstream/877217;
Nearest TSS
ENST00000595228/Upstream/9528;
ENST00000577241/Downstream/69582;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/196950
,
chr17-CpG: 60/Downstream/395836
Upstream sequence
gaccccagagctcatacctttaTCTTTCTCATCAAAAACCACTGGTTGGATGAGTACCTCTCTGGGAAGAAAGGGCTGCATGACCCTGTGTGCTATTACC
Downstream sequence
CACCTGTTGGCCGCCAAGGCTGATACCTGGCAGGAAGCCCTCATTCACAGGGCAGAAGGCTCAGTGAAATAAACAGGCACCCAAGGGCTAAGTGGAGAGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL84
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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