Basic Information
VIS ID
TVIS44009693
Fusion event
HTLV-1-LOC107985239 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
185601295/185632163 (Hg38)
End
185601295/185632163 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107985239
Nearest miRNA
hsa-mir-101-1/Upstream/5193773; hsa-mir-1182/Downstream/7084165;
Nearest TSS
ENST00000473358/Upstream/3636; ENST00000569292/Downstream/22839;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/314929, chr1-CpG: 69/Downstream/742829
Nearby gene
LINC01350(No orient, 3675)
Upstream sequence
ACTATTTTTTCTCTGTTTCACTGATTTTTAATTTGGCAtgtgacagaaagataaatcttggggccctcaaatcactaagctaaagggaaaagtcaagctg
Downstream sequence
ggaactgctcagggccaacctgcctgccattctattcaaagtcacccctctgctcactgagataaatgtatatctgattgtctccttggagaggctaatc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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