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TVIS44009720
Basic Information
VIS ID
TVIS44009720
Fusion event
HTLV-1-PDE3A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
20664594/20511660 (Hg38)
End
20664594/20511660 (Hg38)
Orient
+
Location type
Intronic
Target gene
PDE3A
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-128-3p
;
hsa-mir-211-5p
;
hsa-mir-3680-3p
;
hsa-mir-4666b
;
hsa-mir-5011-3p
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-3915
;
hsa-mir-1224-5p
;
hsa-mir-6797-3p
;
hsa-mir-6076
;
hsa-mir-3928-3p
;
hsa-mir-5582-3p
;
hsa-mir-8055
;
hsa-mir-129-5p
;
hsa-mir-4776-3p
;
hsa-mir-1304-5p
;
hsa-mir-4677-5p
;
hsa-mir-192-3p
;
hsa-mir-2116-5p
;
hsa-mir-22-5p
;
hsa-mir-3613-3p
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-8485
;
hsa-mir-7150
;
hsa-mir-4736
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-7843-3p
;
hsa-mir-5585-5p
;
hsa-mir-3191-5p
;
hsa-mir-548ax
;
hsa-mir-548ao-5p
;
hsa-mir-942-5p
;
hsa-mir-5588-5p
;
hsa-mir-4799-3p
;
hsa-mir-4720-5p
;
hsa-mir-3128
;
hsa-mir-6824-3p
;
hsa-mir-6764-3p
;
hsa-mir-330-5p
;
hsa-mir-326
;
hsa-mir-518c-5p
;
hsa-mir-6814-5p
;
hsa-mir-3614-3p
;
hsa-mir-7849-3p
;
hsa-mir-6818-3p
;
hsa-mir-4753-3p
;
hsa-mir-6873-3p
;
hsa-mir-377-3p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-130b-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6846-3p
;
hsa-mir-4743-3p
;
hsa-mir-6888-3p
;
hsa-mir-3182
;
hsa-mir-3120-5p
;
hsa-mir-1237-3p
;
hsa-mir-607
;
hsa-mir-3671
;
hsa-mir-361-5p
;
hsa-mir-3171
;
hsa-mir-2115-3p
;
hsa-mir-1265
;
hsa-mir-5692a
;
hsa-mir-106a-3p
;
hsa-mir-6844
;
hsa-mir-4684-3p
;
hsa-mir-103a-2-5p
;
hsa-mir-8066
;
hsa-mir-1267
;
hsa-mir-3147
;
hsa-mir-367-5p
;
hsa-mir-4328
;
hsa-mir-4425
;
hsa-mir-450a-1-3p
;
hsa-mir-4652-3p
;
hsa-mir-4747-5p
;
hsa-mir-5196-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/2838266; hsa-let-7i/Downstream/3700761;
Nearest TSS
ENST00000382841/Upstream/141398;
ENST00000544307/Downstream/60204;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/141472
,
chr12-CpG: 97/Downstream/39931
Upstream sequence
tataaaataaatattcatgatcctgtactaatagaaatgattaaatagatgggctaaatagctgtctcttatgtaataaaattccaaatagcttatgtgg
Downstream sequence
atattgtcctccttaaggatgtatagtgtaactcgccattccttaagtgtgggctactcacagtggttccttccaaagagagacttgggcaaagtcttct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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