Basic Information
VIS ID
TVIS44009748
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
34357658/33888452 (Hg38)
End
34357658/33888452 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/2873710; hsa-mir-1185-1/Downstream/3063857;
Nearest TSS
ENST00000550708/Upstream/153211; ENST00000555922/Downstream/42884;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/87220, chr14-CpG: 98/Downstream/61850
Nearby gene
EGLN3(-35763) ;
Nearest cancer related gene
EGLN3(TSG, -35763) ;
Upstream sequence
CGAGATAAGAGCCTAGATGTGAAATGGCAAAGGCCTATTTATAGTAGCAAAGAGAATGAAAGGGAAGGAATACAAATGGAGATGTATTTTAAGTTAACTt
Downstream sequence
aacccaaatgtcctcaggcctcaccattctgtggctcaacattcaggcaacagtaatacctcagtttccctaggtcatcacttccacctgctgatgtaaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate