Basic Information
VIS ID
TVIS44009776
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
22005196/24425232 (Hg38)
End
22005196/24425232 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/103486; hsa-mir-122/Downstream/2166235;
Nearest TSS
ENST00000575820/Upstream/23079; ENST00000578221/Downstream/1384;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/27310, chr18-CpG: 63/Downstream/1114
Nearby gene
IMPACT(+1413) ;
Upstream sequence
tgcctatagtcctagctactaggggagctgaggcaggaagattgcttgagcccaggagGTTATAGTGACTTATGCTGATGAACCAAATATATGACAGTGG
Downstream sequence
TCTCATAAGACCACTTGCATGTCCAATACCATATCTGTAATATGGTATTTGTACTACCATACATTATGGTATttgtactaccatatttgtactgtacctt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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