Basic Information
VIS ID
TVIS44009832
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
34065413/34063791 (Hg38)
End
34065413/34063791 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA4D
Nearest miRNA
hsa-mir-12113/Upstream/5244123; hsa-mir-1243/Downstream/2362575;
Nearest TSS
ENST00000502981/Upstream/23898; ENST00000514737/Downstream/195336;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/3340571, chr4-CpG: 100/Downstream/2180218
Nearby gene
LOC101928622(No orient, 23898)
Upstream sequence
ATGTATGCCTACTTGAGCATTTACAGCTGTGGAGAGGAACTGCTCTTATAGATACTTTACACACTACATGAACATTTTGAGGTGAAGATAAATGAAGGTC
Downstream sequence
AGCACATATCTTTGCAACATATTATTTAACAGGAGAGTAATACTTCTGATAAAAGTTATTTACATAAACTGTTTCTATCCTATATTTAGATACAATAAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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