Basic Information
VIS ID
TVIS44009843
Fusion event
HTLV-1-OTUD4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
End
146082659/145161507 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-30b-5p ; hsa-mir-183-5p ; hsa-mir-101-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-18a-3p ; hsa-mir-6885-3p ; hsa-mir-3163 ; hsa-mir-4255 ; hsa-mir-130b-5p ; hsa-mir-5571-5p ; hsa-mir-2681-5p ; hsa-mir-4753-3p ; hsa-mir-6809-3p ; hsa-mir-6875-3p ; hsa-mir-6516-5p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-219b-3p ; hsa-mir-6513-3p ; hsa-mir-219a-2-3p ; hsa-mir-455-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-4714-3p ; hsa-mir-4272 ; hsa-mir-4760-3p ; hsa-mir-498 ; hsa-mir-4778-3p ; hsa-mir-4282 ; hsa-mir-3591-5p ; hsa-mir-1256 ; hsa-mir-4796-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-142-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-106a-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-5682 ; hsa-mir-767-5p ; hsa-mir-3662 ; hsa-mir-6871-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-6807-5p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p ; hsa-mir-19a-3p ; hsa-mir-219a-1-3p ; hsa-mir-3125 ; hsa-mir-31-5p ; hsa-mir-3646 ; hsa-mir-3675-5p ; hsa-mir-3916 ; hsa-mir-4466 ; hsa-mir-4699-5p ; hsa-mir-4706 ; hsa-mir-4709-3p ; hsa-mir-4723-5p ; hsa-mir-4749-5p ; hsa-mir-486-3p ; hsa-mir-5698 ; hsa-mir-570-3p ; hsa-mir-675-5p ; hsa-mir-6795-5p ; hsa-mir-6825-5p ; hsa-mir-6859-5p ; hsa-mir-6870-5p ; hsa-mir-6887-5p ; hsa-mir-7106-5p ; hsa-mir-7111-5p ; hsa-mir-744-5p ; hsa-mir-766-5p
Nearest miRNA
hsa-mir-12113/Upstream/1817972; hsa-mir-1305/Downstream/1247076;
Upstream sequence
TGTATTGCACATATCTTTACTGGTTACCACTAGCTTAAGAGCAGAGGAAAAAGCTGTCACAAGCCCAGCACCACTGCTTTATGACTGATCTGTACTTTGC
Downstream sequence
CAGAACGGATGATATAAAAGAAACTGGTAGGAAGGGTCACTGCTCTTCTACAGCAGGAATTCTCACACAGAAGAAGGGCAAAGGGAATTCATATGcccag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate