Basic Information
VIS ID
TVIS44009846
Fusion event
HTLV-1-ANXA10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
169030326/168109175 (Hg38)
End
169030326/168109175 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANXA10
Nearest miRNA
hsa-mir-12113/Upstream/2722838; hsa-mir-1305/Downstream/3077009;
Nearest TSS
ENST00000502981/Upstream/16660; ENST00000503003/Downstream/4156;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2234986, chr4-CpG: 27/Downstream/209223
Upstream sequence
CTCAGTGAAAACTGAATTATAAAGGGACCAATTTTAAAATCTTGTTATGGTGCTACATGAACTCTTTGATGTTTCCCACATTTTTTTTCTGCTATGTACC
Downstream sequence
CATCAGATGAGAATTTCTACCAACCCTCACTTTCCAGAAAGAAGATCAATGTATGTTTGGTGCAGAGCAACCCATAACTGATTTCTGTTCAACATACCAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate