Basic Information
VIS ID
TVIS44009862
Fusion event
HTLV-1-LOC101929555 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
40968209/41000470 (Hg38)
End
40968209/41000470 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA6H
Target gene
LOC101929555
Nearest miRNA
hsa-mir-1236/Upstream/1926089; hsa-mir-10398/Downstream/598253;
Nearest TSS
ENST00000381078/Upstream/285107; ENST00000470917/Downstream/32517;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/400629, chr6-CpG: 39/Downstream/27593
Upstream sequence
TTGCAGTGGCAAGTACAGAGAGGGCATGAGGTGGGCATCCCTCTCATCTGGGCCACGTGACCACTACGGAATGTGTCCCTACTCTAGGTCTGATAAGACT
Downstream sequence
TCCTCCTAAAAGGGAAGCCCaggaactagaggcaaggtgtgggggaaggtggtaaaaagcagactaggccacctctccaaggcagacctagctcaggctt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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