Basic Information
VIS ID
TVIS44009898
Fusion event
HTLV-1-MIR6130 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
77089103/74474187 (Hg38)
End
77089103/74474187 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MIR6130
Nearest miRNA
hsa-mir-101-2/Upstream/3664103; hsa-let-7a-1/Downstream/9495561;
Nearest TSS
ENST00000422679/Upstream/102656; ENST00000396204/Downstream/23178;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/2108359, chr9-CpG: 43/Downstream/22675
Upstream sequence
AAGAGTTTAGAAATATAGTTTTTCAAAAGGCAAATGATACATaataagtcctcacttaacatcatagataggatcttgaaactgtgactttaagcagaat
Downstream sequence
gatgtgtaacaaaatcaatacttttctcatcaatgttatcacaaaataatgttaattgagggcagcagtagcttatttcacttatagtcttggtttctaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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