Basic Information
VIS ID
TVIS44009937
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
52817096/55149865 (Hg38)
End
52817096/55149865 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/1912675; hsa-mir-122/Downstream/329356;
Nearest TSS
ENST00000575820/Upstream/25559; ENST00000587660/Downstream/79090;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/190247, chr18-CpG: 80/Downstream/437957
Nearby gene
RNA5SP459(-3220) ;
Upstream sequence
tggacaagtttttctttcacaggtgttccatcaaatactttcccttatctctatctctgctctgctcattctttaatccctgtggccaaggaggggtagg
Downstream sequence
atacacttactgttttgagccaatcaggcatcacccctaaaagtagaactagggacaacagtgagcaaactcacacagagaagaggggacaggcaaattc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate