Basic Information
VIS ID
TVIS44009941
Fusion event
HTLV-1-UBASH3A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
43835586/42415477 (Hg38)
End
43835586/42415477 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBASH3A
Nearest miRNA
hsa-let-7c/Upstream/668636; hsa-mir-5692b/Downstream/535451;
Nearest TSS
ENST00000624081/Upstream/11560; ENST00000454800/Downstream/80531;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/109271, chr21-CpG: 58/Downstream/80691
Upstream sequence
GGCTGTGCAGCCTCAGTGCCCCAGCTTTCCTAGAGACCGTGGGAGCTTCCCATTTGCCTCTAAAGGCTCACCTCTCACGTGGGAGACAGCAGTGAGCCCC
Downstream sequence
AACTTCGGGGCTCCAGGGAAAGGCTTGCATCAACCTTGACCTTTTTTAGGGGGTGAGCAGATCCTGTTTGTAAGTGCCCTGCCGTGGAGTGGGGGCAGGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate