Basic Information
VIS ID
TVIS44010007
Fusion event
HTLV-1-CLRN1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
150796612/151078825 (Hg38)
End
150796612/151078825 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA3D
Target gene
CLRN1-AS1
Nearest miRNA
hsa-let-7g/Upstream/16640919; hsa-mir-1224/Downstream/487051;
Nearest TSS
ENST00000440867/Upstream/105826; ENST00000469768/Downstream/6872;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/299180, chr3-CpG: 223/Downstream/6384
Upstream sequence
TATAATTTTCATCAGATGTAACCCATCCTAACAGGTTAGTTACAATCTGAAACTAACTGATGATAAAGACTGGATCCTTAACTGGTTAACAATAAAAAAG
Downstream sequence
TAGTAACATAATCAATTATTGTATAACTGAAAAGTAATCTCTCTCTCTCTCCTTTCCCAACAGGAAAGTCTGAAGCCAGGCCTGCTTAGCAGAGGTCTCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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