VISDB Viral Integration Site DataBase

VIS ID

TVIS44010049

Fusion event

HTLV-1-PHACTR4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p35.3

Reference genome

Start

End

28795711/28469200 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-361-5p ; hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-mir-181a-5p ; hsa-mir-222-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-5695 ; hsa-mir-454-5p ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-202-3p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7162-3p ; hsa-mir-1281 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6888-5p ; hsa-mir-1294 ; hsa-mir-22-3p ; hsa-mir-2278 ; hsa-mir-3065-3p ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3184-5p ; hsa-mir-3190-3p ; hsa-mir-3196 ; hsa-mir-3617-3p ; hsa-mir-3656 ; hsa-mir-383-3p ; hsa-mir-3976 ; hsa-mir-423-5p ; hsa-mir-4459 ; hsa-mir-4710 ; hsa-mir-4722-5p ; hsa-mir-6079 ; hsa-mir-6134 ; hsa-mir-6165 ; hsa-mir-671-5p ; hsa-mir-6816-5p ; hsa-mir-6828-5p ; hsa-mir-6894-5p ; hsa-mir-7854-3p

Nearest miRNA

hsa-mir-12136/Upstream/1914607; hsa-mir-101-1/Downstream/2269956;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/98980, chr1-CpG: 78/Downstream/48941

Nearest cancer related gene

PHACTR4(TSG, No orient, 0)

Upstream sequence

aggactctcttttattctaaaattacaaccttcctaatcctttggtgttaaaatgccatttctttcacaaaaggattatgatcataaatggtttacttaa

Downstream sequence

tatcaagccttatttggaaatcttagaaaatgacaacctcaaaaaaacactagaaaaaaaaccaacaatctgaggttgatcaagatttttgttattgttt