Basic Information
VIS ID
TVIS44010050
Fusion event
HTLV-1-MIR3659HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
38556688/38091016 (Hg38)
End
38556688/38091016 (Hg38)
Orient
-
Location type
Intronic
Target gene
MIR3659HG
Nearest miRNA
hsa-mir-12136/Upstream/1687; hsa-mir-101-1/Downstream/2663339;
Nearest TSS
ENST00000473358/Upstream/43591; ENST00000634732/Downstream/49577;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/43046, chr1-CpG: 42/Downstream/487477
Nearby gene
MIR3659(+1687) ;
Upstream sequence
CTGGGACCACTGTAGGAGAAGGGAGAGAGGAGAGACCTGTCATGCAGAGGCCTGTGGGTGGGGTAAATAGGTTAACCTTTTAGGGAAGACAGTGGGAAGG
Downstream sequence
CATGGAAGGATTGTGCAAGTGTGGGGGCTGCCATGTCAGGTGTGTACTTTAGAAAACCTTTCCTCTTCTTGCACATGTCCATTGTCAAGGGGTCCCTGGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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