Basic Information
VIS ID
TVIS44010051
Fusion event
HTLV-1-LOC105378797 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
72834951/72369268 (Hg38)
End
72834951/72369268 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
LOC105378797
Nearest miRNA
hsa-mir-101-1/Upstream/1301552; hsa-mir-11399/Downstream/4690875;
Nearest TSS
ENST00000473358/Upstream/86534; ENST00000418078/Downstream/395763;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/85215, chr1-CpG: 24/Downstream/1828874
Nearby gene
NEGR1(-86674) ;
Upstream sequence
aacatgttgttagctggttattatgcagatttgattttgtggtttctttatactgtcaatggcttatgtacttaagtctgtttttgtggtggccagtaat
Downstream sequence
gctctttcctttccatatttagcactcccttaaggacctcttgggtggtattaacaaattcccttagcatttgcttatctgaaaaggatcttatttctcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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