Basic Information
VIS ID
TVIS44010054
Fusion event
HTLV-1-NTNG1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
107711069/107168447 (Hg38)
End
107711069/107168447 (Hg38)
Orient
-
Location type
Intronic
Target gene
NTNG1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-129-5p ; hsa-mir-2054 ; hsa-mir-3613-5p ; hsa-mir-6885-3p
Nearest miRNA
hsa-mir-101-1/Upstream/6887139; hsa-mir-11399/Downstream/728776;
Nearest TSS
ENST00000473358/Upstream/19853; ENST00000477948/Downstream/92356;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/26606, chr1-CpG: 22/Downstream/312163
Upstream sequence
TTATTAATCGATGAAGTAAGACACTACATCTAGAAGAGTATTTTTCTGATATATAAATCTTATTTGTTTTTAATATTCTGGACAGTTTAAAATATTTCTC
Downstream sequence
TCTCTCAGTAGAAACTTTTCCATATCTGCTTTAACTTGACACTATGCCCCTGTCTACAACTGTTCATGAGCATCTCTGCTCCCTTGAGGAAAATAGAAGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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