Basic Information
VIS ID
TVIS44010057
Fusion event
HTLV-1-LOC107985212 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
158429574/158459784 (Hg38)
End
158429574/158459784 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107985212
Nearest miRNA
hsa-mir-101-1/Upstream/1523540; hsa-mir-1182/Downstream/1440195;
Nearest TSS
ENST00000473358/Upstream/33547; ENST00000289451/Downstream/1790;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/278071, chr1-CpG: 44/Downstream/711628
Nearby gene
OR10K1(+5778) ;
Upstream sequence
TCCCTTTTAGATATTCACCATCCATACACATCCTTCTGTTGATGTTTAAATTTCCAAACAGTAATAACGAATATAACGAAAATACATCTCACATAAAGAG
Downstream sequence
GTACCCACATTTATCTCTAAAAATGAAACAATAAATTATTTGATAGCCTTTTCTTTGTAGATGGAATTATAATGTTTTGTAACATCAACACACCTTATAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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