Basic Information
VIS ID
TVIS44010066
Fusion event
HTLV-1-LINC02660 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
3962957/3920765 (Hg38)
End
3962957/3920765 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02660
Nearest miRNA
hsa-mir-5699/Upstream/1844676; hsa-mir-107/Downstream/70395;
Nearest TSS
ENST00000439456/Upstream/86815; ENST00000432452/Downstream/13754;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/134831, chr10-CpG: 60/Downstream/905168
Nearby gene
MIR6078(No orient, 70395)
Upstream sequence
TTTTCCAAATGTTATTTGAGATTATGGATGAAAGAAAACGTGGTCATCGTAAGTTCTCTCCTCTTGTTTCTCAGTGCTGCAGTCCACTGTACACATCAAC
Downstream sequence
TATTTAAGAATTTCAGAGTGCAGAATATAGAACAATATACTCTGTTTATAAAGTAAAGCTTACACCCACTGAAACAGAATGGCATTTAGCAGTATTTTGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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