Basic Information
VIS ID
TVIS44010072
Fusion event
HTLV-1-ZNF37BP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
43012762/42517314 (Hg38)
End
43012762/42517314 (Hg38)
Orient
-
Location type
ncRNA_exonic
Fragile sites / regions
FRA10G
Target gene
ZNF37BP
Nearest miRNA
hsa-mir-1265/Upstream/6876062; hsa-mir-107/Downstream/480249;
Nearest TSS
ENST00000439456/Upstream/41686; ENST00000439913/Downstream/77353;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/39809, chr10-CpG: 67/Downstream/34822
Upstream sequence
ACTCAGATATTGTTTGCAGTTGTGACAAGGTACAATGAATCTCTGGTATGACCTTGTTTCCAGGGCTTTTACTGATGGCATGTTCATGAAAGGACCAACC
Downstream sequence
CACTGGCACTTCCTAAGGTCTAATCATTTCTCCTCCATATTGCAAAATGCAAAACAAAACAAAAATCCTACTTGTTTTCTTCTCAAAttagcttttcagc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate