Basic Information
VIS ID
TVIS44010091
Fusion event
HTLV-1-LINC02750 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.12
Reference genome
GRCh37/hg19
Start
50281695/50322524 (Hg38)
End
50281695/50322524 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02750
Nearest miRNA
hsa-mir-129-2/Upstream/2225666; hsa-let-7a-2/Downstream/6421349;
Nearest TSS
ENST00000527297/Upstream/23906; ENST00000319760/Downstream/4281474;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/23923, chr11-CpG: 94/Downstream/5550068
Nearby gene
LOC441601(-24062) ;
Upstream sequence
ttggctcactgcaacctccacctccttggttcaagtgattctcctgcctcagtctccctaaggcaggcctcttaagtgttgggattacaggcatgagcca
Downstream sequence
ccactcccTCCcagtctactctcagtacaacagttagaacaatccttttacagtgtaattcagatcatgtttacccctctgttcaaattctccagcggct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate