Basic Information
VIS ID
TVIS44010108
Fusion event
HTLV-1-LOC643339 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
93725690/93331914 (Hg38)
End
93725690/93331914 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LOC643339
Nearest miRNA
hsa-let-7i/Upstream/6586765; hsa-mir-1178/Downstream/1229875;
Nearest TSS
ENST00000382841/Upstream/116235; ENST00000550056/Downstream/45794;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/402192, chr12-CpG: 85/Downstream/45775
Upstream sequence
tcgctcttcctgcccaggctggagtgcaagggcacaatctcggctcactgcaacctctgcctcccaggttcaagcaattctcctcctcaacttcccaagt
Downstream sequence
agctgggattacaggcgcctgccaccacacctggctaatttttgtatttttagtagagacagggttttaccatgttggccaagctcatctcgaactcctg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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