Basic Information
VIS ID
TVIS44010136
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
53421723/53129526 (Hg38)
End
53421723/53129526 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02490 ; LOC107983981
Nearest miRNA
hsa-mir-10393/Upstream/852326; hsa-mir-11181/Downstream/2243414;
Nearest TSS
ENST00000557528/Upstream/13161; ENST00000561210/Downstream/411554;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/323247, chr15-CpG: 33/Downstream/629932
Nearby gene
ONECUT1(-339514) ;
Upstream sequence
TGGCAATCGTAGCTCTGTAAGCCTGGCCTGCTCACGTGGAAGTAAATTATTTGATGAGCTGGGGAAATATAAGCAGTTTGTGTGGATTAAAAGGAAATCC
Downstream sequence
TCACCCAAACTATATCTTTAAAAATTATCTAGATAATTCAGGTGAAAGCAGGCTTTCTCCCTTGTGAATTATTAAAGTAATTGATTACATCCATCTGCTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate